Traditional opinion is that periodontal disease is caused by excess bacteria from poor oral hygiene. This is thougth to cause an inflammatory process that leads to the destruction of bone and tissue attatchment to teeth. So the theory goes . . .
Dentistry has recognized that a number of factors other than hygiene play a role in the development of periodontal disease like diet, stress, abnormal biting forces. Yet, to my astonishment, I have never seen an article that suggests that the periodontal disease process is effected systemically by an orthopedic malalignment of the jaw, even though the primary neurotransmitter (Substance P) of the trigeminal nerve is known to mediate the
inflammatory process! [The defect in orthopedic malalignment that causes the trigeminal nerve tone to become elevated is not occlusion, but dysfunction of the proprioceptive mechanism within the brain (mesencephalic nucleus). This leads to a hypervigilant state, causing excess secretion of Substance P.] Substance P is also known to effect the permeability of calcium across the cell membrane which could account for the bone loss seen in periodontal disease.
Clinically, this manifests with the observation that numerous periodontal pockets deminish considerably with jaw orthopedic therapy. Likewise, periodontal inflammation, both in isolated locations and systemically, typically will disappear.